Jobs at ICON plc

Conducts independent clinical study start-up, monitoring, documentation, regulatory submissions, and site close-out for Phase I–III/IV trials. Ensures compliance with ICH-GCP and applicable regulations, reviews medical data, manages sponsor queries and study costs, and may train fellow CRAs. Requires frequent international and domestic travel, including driving.

Leads cross-functional project and program delivery from initiation through completion, managing plans, timelines, budgets, resources, risks, stakeholders, reporting, and quality. Coordinates teams, resolves issues, monitors performance, communicates progress to senior management, and supports team capability development and continuous improvement. The role requires strong leadership, organization, communication, adaptability, and approximately 30% travel.

Prepare and execute invoicing and reporting for assigned accounts; negotiate site contracts, budgets, payment terms, ancillary agreements and amendments; partner with Study Startup, CROs and Clinical Operations to improve SB&C metrics; apply standards, use industry tools and data to provide budget and contract feedback aligned with fair market value; track negotiations, escalate delays, and support resolution of site activation issues.

Leads clinical data science initiatives supporting clinical trial analysis and strategic decision-making. Responsibilities include designing data science strategies, identifying analytical requirements, overseeing statistical models and tools, mentoring team members, and communicating insights through reports and presentations. Requires clinical research data analysis experience, statistical software and visualization expertise, strong analytical and leadership skills, and approximately 15% travel.

Lead and execute site selection and study start-up activities for assigned Phase I-IV sites, manage submissions and site document collection, ensure timelines/KPIs and TMF readiness, coordinate with study teams, support vendor setup, contracts, and audits, and prepare sites for Green Light following ICH-GCP and local regulations.

The Senior Study Manager oversees clinical trial operations, managing teams, vendor interactions, budgets, timelines, and ensuring compliance and quality control throughout the study process.

The Senior Study Manager will oversee clinical trial activities, manage operational deliverables, vendor interactions, and ensure compliance with protocols and budgets while leading the Clinical Trial Team.

The Informed Consent Writer is responsible for preparing health literate informed consent documents for clinical trials across multiple therapeutic areas, ensuring clarity and compliance with regulations.

Monitor clinical study progress at investigative sites or remotely to ensure trials follow protocol, SOPs, ICH-GCP and regulatory requirements. Conduct site monitoring, source data verification, regulatory document review, and communicate with study teams to support data integrity and patient safety.

The Manager oversees contracts management, negotiating agreements, ensuring compliance, and supporting project teams with contract-related issues.

Manage review, negotiation, and administration of clinical trial and vendor contracts. Assess contract risks, ensure regulatory compliance, maintain contract records, and advise internal teams on interpretation and dispute resolution.

Manage site start-up and activation tasks for assigned clinical trial sites, including collection and review of essential documents, eTMF accuracy, ICD/ICF review, tracking actions and timelines, escalating delays, and collaborating with CROs and internal teams to improve site activation metrics and resolve issues.

Lead and manage oncology clinical trials or a portfolio, serving as primary client liaison. Direct cross-functional teams and vendors, ensure contractual deliverables, timelines, budgets and risk mitigation. Prepare project financials and projections, participate in bid defense, and provide performance feedback to improve team delivery.

Manage site contracting and invoicing for assigned accounts: negotiate clinical trial agreements, budgets, payment terms and amendments; partner with internal startup, CRO and operations teams; apply SB&C standards; use industry tools and data to provide budget/contract feedback; track negotiations and timelines; escalate and resolve activation issues.

The Country Study Operations Manager oversees clinical trial operations across countries, ensuring compliance and timely execution, while managing budgets and resources effectively.

Oversee and monitor clinical trial sites to ensure GCP and protocol compliance, conduct site visits, resolve issues, ensure data integrity, train site staff and CRAs, collaborate with cross-functional teams, and maintain stakeholder relationships to support trial execution.

As a Global Study Manager, you will lead projects, manage cross-functional teams, and ensure successful project execution while mentoring team members.

Lead Clinical Data Science project teams to plan, set up, maintain and close clinical data systems. Provide technical review, support sales/bid defense, oversee system integration and vendor interactions, manage timelines/budgets, perform CRF and UAT peer review, and act as primary contact for internal and external stakeholders.

The Study Start Up CRA is responsible for site selection, start up activities, ensuring compliance with relevant regulations, and collaborating with various stakeholders to meet study timelines.