Jobs at ICON plc

Manage and analyze clinical trial contracts and vendor agreements, negotiate terms, assess contract risk and compliance, maintain contract records in management systems, and advise internal teams on contract interpretation and dispute resolution.

The Country Study Operations Manager oversees clinical trial operations across countries, ensuring compliance and timely execution, while managing budgets and resources effectively.

Lead and coordinate country-level clinical study operations from start-up through close, oversee pCRO/local teams, ensure regulatory and quality compliance, manage risks and timelines, support site activation, recruitment and data deliverables, and provide local intelligence to global teams.

Support management and execution of clinical trials by handling administrative and operational tasks: manage documentation, assist regulatory submissions, coordinate sites and meetings, monitor trial progress, and liaise with cross-functional teams and site staff to ensure compliance and timely delivery of study materials.

Lead design, deployment and management of eCOA/ePRO systems for decentralized trials. Serve as sponsor SME and project manager, define requirements, oversee UAT, vendor selection and oversight, resolve system issues, integrate eCOA data with CTMS and data warehouses, ensure documentation and audit readiness, provide training, and coordinate cross-functional delivery within timelines and budgets.

Lead and coordinate country-level clinical study operations from startup through close: manage country teams and pCROs, ensure regulatory/quality compliance, oversee site activation, recruitment, risk mitigation, PTMF/ISF completeness, vendor management, and implementation of trial technologies to meet timelines and deliverables.

The Senior Study Manager oversees clinical trial operations, managing teams, vendor interactions, budgets, timelines, and ensuring compliance and quality control throughout the study process.

The Senior Study Manager will oversee clinical trial activities, manage operational deliverables, vendor interactions, and ensure compliance with protocols and budgets while leading the Clinical Trial Team.

The Informed Consent Writer is responsible for preparing health literate informed consent documents for clinical trials across multiple therapeutic areas, ensuring clarity and compliance with regulations.

Monitor clinical study progress at investigative sites or remotely to ensure trials follow protocol, SOPs, ICH-GCP and regulatory requirements. Conduct site monitoring, source data verification, regulatory document review, and communicate with study teams to support data integrity and patient safety.

Lead and manage global clinical study delivery: develop and execute project plans, lead cross-functional teams, define scope, mentor staff, produce documentation and reports, integrate best practices, and support strategic planning to meet timelines and quality objectives.

Edit and proofread clinical and regulatory documents, ensure compliance with guidelines, mentor junior staff, fact-check data, implement SOPs, and collaborate with writers to improve scientific communications.

Coordinate site activations and maintenance across studies; collect and review Critical Document Packages (CDPs); forecast activation dates; liaise with sites, sponsors, and internal stakeholders; ensure regulatory/IRB submissions and TMF quality; manage translations, CTAs/budgets support, escalate issues, and mentor team members while driving process improvements and KPI achievement.

Manage site start-up and activation tasks for assigned clinical trial sites, including collection and review of essential documents, eTMF accuracy, ICD/ICF review, tracking actions and timelines, escalating delays, and collaborating with CROs and internal teams to improve site activation metrics and resolve issues.

Lead Clinical Data Science project teams to plan, set up, maintain and close clinical data systems. Provide technical review, support sales/bid defense, oversee system integration and vendor interactions, manage timelines/budgets, perform CRF and UAT peer review, and act as primary contact for internal and external stakeholders.

The Study Start Up CRA is responsible for site selection, start up activities, ensuring compliance with relevant regulations, and collaborating with various stakeholders to meet study timelines.

Oversee and monitor clinical trial sites to ensure GCP and protocol compliance, conduct site visits, resolve issues, ensure data integrity, train site staff and CRAs, collaborate with cross-functional teams, and maintain stakeholder relationships to support trial execution.

As a Global Study Manager, you will lead projects, manage cross-functional teams, and ensure successful project execution while mentoring team members.

Accountable for end-to-end country-level trial delivery for oncology and multi-therapeutic studies: vendor and vendor PO management, local milestones, resourcing, inspection readiness, cross-functional coordination with LTMs/LSMs/CTAs/SCMs, reporting to Functional Manager and Global Trial Leader, and supporting documentation, training, and ad hoc country-level issue resolution.